In vitro INHIBITION OF BRAIN MITOCHONDRIAL MONOAMINE OXIDASE BY 6-HYDROXYDOPAMINE
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چکیده
منابع مشابه
Inhibition of monoamine oxidase by stilbenes from Rheum palmatum
Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-O-β-D-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). Anti-monoamine oxidase (MAO) activities of compounds 1–8 were tested. Compounds 1 and 8 showed sig...
متن کاملInhibition of monoamine oxidase by stilbenes from Rheum palmatum
Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-O-β-D-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). Anti-monoamine oxidase (MAO) activities of compounds 1–8 were tested. Compounds 1 and 8 showed sig...
متن کاملMitochondrial Monoamine Oxidase
Inhibitions of the relatively highly purified flavoenzyme, bovine kidney mitochondrial monoamine oxidase, previously described in Paper I (Erwin, V. G., and Hellerman, L., J. Biol. Gem., 242, 4230 (1967)), by several agents of current interest have been investigated. The inhibitors include Nmethyl-N-(Z-propynyl)benzylamine (pargyline), (+)-fransphenylcyclopropylamine (d form of tranylcypromine)...
متن کاملMitochondrial Monoamine Oxidase
Monoamine oxidase of bovine kidney mitochondria has been purified to high specific activity by solubilization with digitonin, ammonium sulfate fractionation, and calcium phosphate gel-cellulose column chromatography. Absorption and fluorescence spectra indicated strongly that mitochondrial monoamine oxidase is a flavoenzyme. Under anaerobic conditions, benzylamine reduced the flavin at 460 rnp ...
متن کاملinhibition of monoamine oxidase by stilbenes from rheum palmatum
seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of rheum palmatem. their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-o-β-d-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). anti-monoamine oxidase (mao) activities of compounds 1–8 were tested. compounds 1 and 8 showe...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1975
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1975.tb07583.x